Scientific Information

There is a myth that natural medicines do not have substantial peer-reviewed chemical trials from credible medical facilities.

This is simply not true. Our research indicates that there are over 500 000 such studies available globally and we are pleased to bring some of the more relevant onces to our reader's attension.

This article hub, the scientific information and research section of Tuck's Discount Vitamins and Wellness Centre, has 518 articles to assist in informed freedom of choice in the health care of our readers.

• Essiac - Unconventional Therapies for Cancer

  PHYSICIANS AND PATIENTS HAVE BEEN FRUSTRATED by the lack of reliable information on unconventional therapies. To help fill this gap in the area of breast cancer therapy, the Canadian Breast Cancer Research Initiative formed a task force to advise it on how best to promote research into unconventional therapies. As part of the work of the task force, a review of the available literature was carried out for each of the following products: Essiac, green tea, Iscador, hydrazine sulfate, vitamins A, C and E, and 714-X. The first article in this series on unconventional therapies for cancer describes the methodology used to obtain and evaluate the information and provides a summary of the findings on Essiac. Subsequent articles will cover the other products. For most of the products reviewed, there has been some indication of possible benefit but no definitive evidence. Innovative and collaborative research needed to meet the information needs of growing numbers of patients and their physicians is now being sponsored by the Canadian Breast Cancer Research Initiative. Open communication between patients and physicians is also necessary for the maintenance of an appropriate therapeutic partnership and for the identification and control of side effects. The Ontario Division of the Canadian Cancer Society, a partner in the Canadian Breast Cancer Research Initiative, supported the preparation of a patient information piece on unconventional therapies to accompany the series. This item will assist patients who are considering such therapies and will promote open communication between patients and their physicians. Elizabeth Kaegi, MB, ChB, MSc, on behalf of the Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative

• Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial.

  Improving calcium and vitamin D nutritional status substantially reduces all-cancer risk in postmenopausal women. Am J Clin Nutr. 2007 Jun;85(6):1586-91. Lappe JM, Travers-Gustafson D, Davies KM, Recker RR, Heaney RP.

• Vitamin D intake and breast cancer risk in postmenopausal women

  Vitamin D is thought to act as a cancer chemopreventive agent. The Iowa Women's Health Study. Cancer Causes Control. 2007 Sep;18(7):775-82. Robien K, Cutler GJ, Lazovich D.

• Vitamin D Deficiency and Risk of Cardiovascular Disease.

  Evidence suggests that vitamin D deficiency may adversely affect the cardiovascular system Circulation published online Jan 7, 2008. Thomas J. Wang, Michael J. Pencina, Sarah L. Booth, Paul F. Jacques, Erik Ingelsson, Katherine Lanier, Emelia J. Benjamin, Ralph B. DAgostino, Myles Wolf and Ramachandran S. Vasan

• Vitamin D - 25-Hydroxyvitamin D Levels and the Risk of Mortality in the General Population.

  The lowest quartile of Vitamin D3 is independently associated with all-cause mortality in the general population Arch Intern Med. 2008;168(15):1629-1637. Melamed ML, Michos ED, Post W, Astor B.

• Coenzyme Q10 - Study on safety and bioavailability of ubiquinol (Kaneka QH(trade mark)) after single and 4-week multiple oral administration to healthy volunteers.

  The safety and bioavailability of ubiquinol (the reduced form of coenzyme Q(10 were evaluated for the first time in single-blind, placebo-controlled studies. Kazunori Hosoe, Mitsuaki Kitano, Hideyuki Kishida, Hiroshi Kubo, Kenji Fujii, Mikio Kitahara Pharmacology and Toxicology Group, Life Science Research Laboratories, Kaneka Corporation, 1-8 Miyamae-machi, Takasa-cho, Takasago-shi, Hyogo 676-8688, Japan

• Sterols/Sterolins - Randomized, placebo-controlled, double blind clinical trial of b-sitosterol in patients with benign prostatic hyperplasia

  Randomized, placebo-controlled, double blind clinical trial of b-sitosterol in patients with benign prostatic hyperplasia Author: R.R. Berges; J. Windeler; H.J. Trampisch; T.H. Senge and the b-sitosterol study group. Source: Lancet, vol. 345, no. 8964, pp. 1529-32, June 1995

• Calcium - Higher levels of calcium counter depressive states.

  Pharmacol Biochem Behav. 1986 Mar;24(3):445-8. Effects of elevated calcium on learned helplessness and brain serotonin metabolism in rats. Trulson ME, Arasteh K, Ray DW. We conclude that elevated levels of calcium enhance learned helplessness and decrease brain serotonin turnover. The relationship between depressive states and calcium homeostasis is worthy of further investigation.

• Green Tea - Preventive effects of drinking green tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention.

  The life-prolonging effects of drinking green tea on cumulative survival was evaluated using the life table. Biofactors. 2000; 13(1-4): 49-54. Nakachi K, Matsuyama S, Miyake S, Suganuma M, Imai K.

• Green tea - Interactive suppression of aberrant crypt foci induced by azoxymethane in rat colon by phytic acid and green tea.

  While green tea has a marginal effect (P < 0.14), phytic acid significantly reduces the incidence of aberrant crypt foci (P < 0.008). The interaction between green tea and phytic acid was significant (P < 0.029 for distal and < 0.0168 for entire colon) and positive, pointing to a synergistic effect of green tea and phytic acid. Carcinogenesis 1997 Oct; 18(10): 2023-6. Challa A, Rao DR, Reddy BS.

• Protein - Dietary Amino Acids Promote Pancreatic Protease Synthesis at the Translation Stage in Rats1

  Amino acids (AA) stimulate translation initiation via interactions between eukaryote initiation factor (eIF) 4E-binding protein 1 (4E-BP1), eIF4E and eIF4G. Dietary AA have been shown to induce pancreatic proteases independently of cholecystokinin in rats

• Scientific Information

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